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1 Covaxin dose to survivor equals 2 doses to uninfected | India Information

NEW DELHI: A single-dose of Bharat Biotech’s Covaxin in individuals who had been contaminated with Covid-19 beforehand generates antibody response just like that supplied by two doses of the vaccine in these with none historical past of the an infection, reveals a pilot examine by the Indian Council of Medical Analysis (ICMR).
The findings are based mostly on preliminary knowledge and have to be confirmed with large-sized cohort research, it mentioned.
The examine assumes significance as a result of if ICMR can validate the preliminary findings by a large-scale examine, it may be instrumental in expediting the protection.
“This examine provides proof in assist of public health-oriented and immunologically sustained vaccine methods. If our preliminary findings are confirmed in giant inhabitants research, a single dose of BBV152 vaccine could also be really helpful to beforehand confirmed SARS-CoV-2 contaminated people in order that the naïve people might attain the bigger advantage of a restricted vaccine provide,” says the brief paper with the findings of the examine printed within the Indian Journal of Medical Analysis.
Nonetheless, the authors underlined that each vaccine doses could be preferrred even for beforehand contaminated people in the long term as a result of prevalence of variants of concern.
Bharat Biotech’s Covaxin is at present administered in a two-dose routine with a spot of 4 to 6 weeks.
The ICMR examine was undertaken to look at SARS-CoV-2–particular antibody responses after day zero (baseline, earlier than vaccination), Day 28 (month 1) and Day 56 post-first dose (month 2) of Covaxin in a gaggle of healthcare professionals in addition to front-line employees.
The antibody response of people with confirmed pre-vaccination SARS-CoV-2 an infection was in contrast with these people with out prior proof of an infection.

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